avermectin - definição. O que é avermectin. Significado, conceito
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O que (quem) é avermectin - definição

DRUGS TO TREAT PARASITIC WORMS AND INSECT PESTS
Avermectine; Avermectins
  • Diagram showing the schematic synthesis of avermectins
  • Organization of the avermectin polyketide synthase

avermectin         
[?e?v?'m?kt?n]
¦ noun Medicine any of a group of macrocyclic compounds isolated from a strain of bacteria, used to destroy parasitic worms.
Origin
1970s: from mod. L. (Streptomyces) averm(itilis), the name of the source bacterium, + ect- + -in1.

Wikipédia

Avermectin

The avermectins are a series of drugs and pesticides used to treat parasitic worms and insect pests. They are a group of 16-membered macrocyclic lactone derivatives with potent anthelmintic and insecticidal properties. These naturally occurring compounds are generated as fermentation products by Streptomyces avermitilis, a soil actinomycete. Eight different avermectins were isolated in four pairs of homologue compounds, with a major (a-component) and minor (b-component) component usually in ratios of 80:20 to 90:10. Other anthelmintics derived from the avermectins include ivermectin, selamectin, doramectin, eprinomectin, and abamectin.

Half of the 2015 Nobel Prize in Physiology or Medicine was awarded to William C. Campbell and Satoshi Ōmura for discovering avermectin, "the derivatives of which have radically lowered the incidence of river blindness and lymphatic filariasis, as well as showing efficacy against an expanding number of other parasitic diseases."